It appears that there are more drugs that cause pain than relieve it. Case in point: Xarelto. Generally known as Rivaroxaban, this drug is as an anticoagulant, a blood thinner that is used to reduce the risk of blood clots and strokes. Lately, however, this "new generation" blood thinner has been linked to an increased risk of hemorrhages, strokes, epidural hematoma, pulmonary embolism, and deep vain thrombosis. The drug does not have an antidote, and in lawsuits filed by people who say they were injured by the drug, former Xarelto users say they were not warned sufficiently about its risks.
Lawsuits have been filed against Johnson & Johnson's subsidiary Janssen Pharmaceuticals, Inc., which allege that the drug's use leads to uncontrollable bleeding as a patient's blood doesn't properly clot, even from minor cuts. Pending lawsuits claim that defendants did not adequately warn patients of Xarelto's side effect. In 2012, the FDA reported that three times more people died from adverse events while on Xarelto compared to other blood thinners such as Warfarin.
One of the lawsuits alleges that Xarelto's once-a-day dosing leaves patients vulnerable to blood clots and strokes for a portion of the day. Other anticoagulants are taken twice daily to improve the balance of the amount of the drug in the body throughout the day. Furthermore, a 2014 study found the amount of Xarelto in a patient's body fluctuated more than three times as much as other comparable anticoagulants taken twice daily.